A Vice-Chancellor’s Forum brought together Caribbean leaders, diplomats, and scholars to discuss the region’s response to significant shifts in U.S. policy under President Donald Trump. The virtual event, featured experts like Professor Jeffrey Sachs, Professor W. Andy Knight, and Ambassador Wayne McCook, who focused on how the Caribbean can bolster its resilience amid rising geopolitical instability. Speakers highlighted Trump’s foreign policy as “neo-imperialism,” marked by protectionist trade measures and anti-migrant rhetoric, posing new challenges for the region. Ambassador McCook underscored the risks of U.S. tariff-based trade policies and urged Caribbean countries to strengthen their internal markets and reduce non-tariff barriers. Professor Knight discussed the declining U.S. engagement with multilateral institutions, suggesting this period of uncertainty could also offer opportunities for Caribbean states to diversify diplomatic strategies, expand supply chains, and assert greater influence globally. Throughout the forum, the consensus was clear: Caribbean nations must unite, deepen regional cooperation, and proactively engage in international affairs to adapt to the evolving global landscape and secure better outcomes, turning challenges into opportunities for growth and autonomy.